Helianorphin-19

Modify Date: 2025-08-25 11:25:06

Helianorphin-19 structure	Common Name	Helianorphin-19
	CAS Number	2883653-86-7	Molecular Weight	1790.21
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈₁H₁₃₂N₂₆O₁₆S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Helianorphin-19

Helianorphin-19 is a potent and selective κ-opioid receptor (KOR) activator with a Ki of 21 nM and an EC50 of 45 nM. Helianorphin-19 exhibits strong KOR-specific peripheral analgesic activity in a mouse model of chronic visceral pain[1].

Name	Helianorphin-19

Description	Helianorphin-19 is a potent and selective κ-opioid receptor (KOR) activator with a Ki of 21 nM and an EC50 of 45 nM. Helianorphin-19 exhibits strong KOR-specific peripheral analgesic activity in a mouse model of chronic visceral pain[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
Target	Ki: 21 nM (KOR) ED50: 45 nM (KOR)[1]
References	[1]. Muratspahić E, et al. Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain. J Med Chem. 2021 Jul 8;64(13):9042-9055.

Molecular Formula	C₈₁H₁₃₂N₂₆O₁₆S₂
Molecular Weight	1790.21

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Helianorphin-19

Use of Helianorphin-19

Names

Helianorphin-19 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.