N-Methylquipazine

Modify Date: 2025-08-26 17:11:05

N-Methylquipazine Structure
N-Methylquipazine structure
Common Name N-Methylquipazine
CAS Number 28614-26-8 Molecular Weight 459.44900
Density N/A Boiling Point N/A
Molecular Formula C22H25N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Methylquipazine


N-Methylquipazine is a 5-HT3 agonist. Has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, does not bind to 5-HT1B sites.

 Names

Name N-Methylquipazine dimaleate,2-(1-N-Methylpiperazinyl)quinolinedimaleate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C22H25N3O8
Molecular Weight 459.44900
Exact Mass 459.16400
PSA 168.57000
LogP 1.41310
InChIKey HOMWNUXPSJQSSU-UHFFFAOYSA-N
SMILES CN1CCN(c2ccc3ccccc3n2)CC1

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles2

More Articles
Binding of arylpiperazines to 5-HT3 serotonin receptors: results of a structure-affinity study.

Eur. J. Pharmacol. 168 , 387-392, (1989)

The binding affinities of a series of arylpiperazine derivatives at [3H]quipazine-labeled central 5-HT3 sites were investigated. Features determined to be important for binding include the N4 piperazi...

The characterization of the effect of locally applied N-methylquipazine, a 5-HT3 receptor agonist, on extracellular dopamine levels in the anterior medial prefrontal cortex in the rat: an in vivo microdialysis study.

Synapse 24 , 313, (1996)

In this study, we examined the effect of n-methylquipazine (NMQ), which is a putative 5-hydroxytryptamine3(5-HT3)receptor agonist, on the extracellular concentrations of dopamine (DA) and one of its m...

 Synonyms

N-Methylquipazine dimaleate salt
N-Methylquipazine
N-METHYLQUIPAZINE DIMALEATE
QUIPAZINE,N-METHYL-DIMALEATE
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