2-(4-甲基-1-哌嗪基)-喹啉

更新时间：2025-08-26 17:11:05

2-(4-甲基-1-哌嗪基)-喹啉结构式	常用名	2-(4-甲基-1-哌嗪基)-喹啉	英文名	N-Methylquipazine
	CAS号	28614-26-8	分子量	459.44900
	密度	N/A	沸点	N/A
	分子式	C₂₂H₂₅N₃O₈	熔点	N/A
	MSDS	N/A	闪点	N/A

2-(4-甲基-1-哌嗪基)-喹啉用途

N-Methylquipazine is a 5-HT3 agonist. Has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, does not bind to 5-HT1B sites.

中文名	2-(4-甲基-1-哌嗪基)-喹啉
英文名	N-Methylquipazine dimaleate,2-(1-N-Methylpiperazinyl)quinolinedimaleate
英文别名	更多

分子式	C₂₂H₂₅N₃O₈
分子量	459.44900
精确质量	459.16400
PSA	168.57000
LogP	1.41310
InChIKey	HOMWNUXPSJQSSU-UHFFFAOYSA-N
SMILES	CN1CCN(c2ccc3ccccc3n2)CC1

海关编码	2933990090

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Binding of arylpiperazines to 5-HT3 serotonin receptors: results of a structure-affinity study.

Eur. J. Pharmacol. 168 , 387-392, (1989)

The binding affinities of a series of arylpiperazine derivatives at [3H]quipazine-labeled central 5-HT3 sites were investigated. Features determined to be important for binding include the N4 piperazi...

The characterization of the effect of locally applied N-methylquipazine, a 5-HT3 receptor agonist, on extracellular dopamine levels in the anterior medial prefrontal cortex in the rat: an in vivo microdialysis study.

Synapse 24 , 313, (1996)

In this study, we examined the effect of n-methylquipazine (NMQ), which is a putative 5-hydroxytryptamine3(5-HT3)receptor agonist, on the extracellular concentrations of dopamine (DA) and one of its m...

N-Methylquipazine dimaleate salt

N-Methylquipazine

N-METHYLQUIPAZINE DIMALEATE

QUIPAZINE,N-METHYL-DIMALEATE