Lerdelimumab

Modify Date: 2023-03-03 06:18:58

Lerdelimumab Structure
Lerdelimumab structure
Common Name Lerdelimumab
CAS Number 285985-06-0 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lerdelimumab


Lerdelimumab (CAT-152) is an IgG4 human anti-TGF-β2 recombinant monoclonal antibody. Lerdelimumab can be used as an anti-scarring agent for glaucoma research[1][2].

 Names

Name Monoclonal antibody 6B1 igg4

 Lerdelimumab Biological Activity

Description Lerdelimumab (CAT-152) is an IgG4 human anti-TGF-β2 recombinant monoclonal antibody. Lerdelimumab can be used as an anti-scarring agent for glaucoma research[1][2].
Related Catalog
In Vitro Lerdelimumab (10 μg/mL) 抑制 TGF-β2 诱导的所有作用,如:抑制 TGF-β2 刺激被膜袋转分化和收缩,诱导被膜袋的 MMP-2 和 -9 的释放[2]。
In Vivo Lerdelimumab (100 μL,1 mg/mL;结膜下注射;在术后第 2、3、4、7、9、11 和 14 天) 明显改善青光眼手术结果,降低角膜副作用的风险[1]。
References

[1]. Mead AL, et al. Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery. Invest Ophthalmol Vis Sci. 2003 Aug;44(8):3394-401.  

[2]. Wormstone IM, et al. TGF-beta2-induced matrix modification and cell transdifferentiation in the human lens capsular bag. Invest Ophthalmol Vis Sci.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties
Top Suppliers:I want be here

No recommended suppliers.


Get all suppliers and price by the below link:

Lerdelimumab suppliers

Lerdelimumab price

Hot Compounds More...
Dichloromethane
CAS#:75-09-2
Polyacrylic acid
CAS#:9003-01-4
sodium carbonate
CAS#:497-19-8
Silicon dioxide
CAS#:7631-86-9
Triethanolamine
CAS#:102-71-6
Demeton
CAS#:126-75-0
Water
CAS#:7732-18-5
4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9
Diclofenac sodium
CAS#:15307-79-6
Budesonide
CAS#:51372-29-3