Gamma-glutamylcysteine TFA

Modify Date: 2024-01-10 14:31:45

Gamma-glutamylcysteine TFA Structure
Gamma-glutamylcysteine TFA structure
Common Name Gamma-glutamylcysteine TFA
CAS Number 283159-88-6 Molecular Weight 364.30
Density N/A Boiling Point N/A
Molecular Formula C10H15F3N2O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Gamma-glutamylcysteine TFA


Gamma-glutamylcysteine (TFA) ((γ-glutamylcysteine (TFA)), an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx). Gamma-glutamylcysteine (TFA) also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) and attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes[1].

 Names

Name Gamma-glutamylcysteine (TFA)

 Gamma-glutamylcysteine TFA Biological Activity

Description Gamma-glutamylcysteine (TFA) ((γ-glutamylcysteine (TFA)), an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx). Gamma-glutamylcysteine (TFA) also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) and attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes[1].
Related Catalog
Target

IL-10

IL-6

IL-1β

TNF-α

References

[1]. Braidy N, et al. The Precursor to Glutathione (GSH), γ-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by Aβ40 Oligomers in Human Astrocytes. Front Aging Neurosci. 2019 Aug 8;11:177.

 Chemical & Physical Properties

Molecular Formula C10H15F3N2O7S
Molecular Weight 364.30
Storage condition -20°C