PARP7-IN-15

Modify Date: 2024-01-10 21:42:17

Use of PARP7-IN-15

PARP7-IN-15 (Compound 18) is a PARP7 inhibitor with IC50 of 0.56 nM, that has antitumor activity[1].

Name	PARP7-IN-15

Description	PARP7-IN-15 (Compound 18) is a PARP7 inhibitor with IC50 of 0.56 nM, that has antitumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	PARP7:0.56 nM (IC50)
References	[1]. Silong Zhang , et al. Exploring the structural-activity relationship of hexahydropyrazino[1,2-d]pyrido[3,2-b][1,4]oxazine derivatives as potent and orally-bioavailable PARP7 inhibitors. Eur J Med Chem. 2023 Oct 8:261:115836.

Molecular Formula	C₂₃H₂₄F₆N₆O₄
Molecular Weight	562.46