UC-764864

Modify Date: 2024-01-21 16:02:04

UC-764864 Structure
UC-764864 structure
Common Name UC-764864
CAS Number 278806-03-4 Molecular Weight 322.42
Density N/A Boiling Point N/A
Molecular Formula C19H18N2OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of UC-764864


UC-764864 is a UBE2N inhibitor. UC-764864 inhibits UBE2N enzymatic activity. UC-764864 has cytotoxic effects and inhibition of UBE2N-dependent signaling in leukemic cells. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates in human AML cell lines[1].

 Names

Name UC-764864

 UC-764864 Biological Activity

Description UC-764864 is a UBE2N inhibitor. UC-764864 inhibits UBE2N enzymatic activity. UC-764864 has cytotoxic effects and inhibition of UBE2N-dependent signaling in leukemic cells. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates in human AML cell lines[1].
Related Catalog
References

[1]. Barreyro L, et al. Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Sci Transl Med. 2022 Mar 9;14(635):eabb7695.  

 Chemical & Physical Properties

Molecular Formula C19H18N2OS
Molecular Weight 322.42