278806-03-4

278806-03-4 structure

Name: UC-764864
Chemical Name: UC-764864
CAS Number: 278806-03-4
Molecular Formula: C₁₉H₁₈N₂OS
Molecular Weight: 322.42
Catalog: Signaling Pathways Metabolic Enzyme/Protease E1/E2/E3 Enzyme
Create Date: 2023-09-20 14:00:19
Modify Date: 2024-01-21 16:02:04
UC-764864 is a UBE2N inhibitor. UC-764864 inhibits UBE2N enzymatic activity. UC-764864 has cytotoxic effects and inhibition of UBE2N-dependent signaling in leukemic cells. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates in human AML cell lines[1].

Name	UC-764864

Description	UC-764864 is a UBE2N inhibitor. UC-764864 inhibits UBE2N enzymatic activity. UC-764864 has cytotoxic effects and inhibition of UBE2N-dependent signaling in leukemic cells. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates in human AML cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> E1/E2/E3 Enzyme
References	[1]. Barreyro L, et al. Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Sci Transl Med. 2022 Mar 9;14(635):eabb7695.

Molecular Formula	C₁₉H₁₈N₂OS
Molecular Weight	322.42