CCP peptide

Modify Date: 2025-08-25 11:24:03

CCP peptide Structure
CCP peptide structure
Common Name CCP peptide
CAS Number 277748-59-1 Molecular Weight 2341.47
Density N/A Boiling Point N/A
Molecular Formula C87H145N41O32S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CCP peptide


CCP peptide is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA)[1][2].

 Names

Name CCP peptide

 CCP peptide Biological Activity

Description CCP peptide is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA)[1][2].
Related Catalog
In Vivo CCP peptide is used as a new antigenic substrate in anti-CCP ELISA to detect anti-citrullinated protein antibodies (ACPAs). The anti-CCP ELISA is extremely specific (98%), with a reasonable sensitivity (68%). The anti-CCP ELISA is very useful for diagnostic and therapeutic strategies in rheumatoid arthritis (RA)[3].
References

[1]. Puszczewicz M, et al. Role of anti-citrullinated protein antibodies in diagnosis and prognosis of rheumatoid arthritis. Arch Med Sci. 2011 Apr;7(2):189-94.

[2]. Söderlin MK, et al. Antibodies against cyclic citrullinated peptide (CCP) and levels of cartilage oligomeric matrix protein (COMP) in very early arthritis: relation to diagnosis and disease activity. Scand J Rheumatol. 2004;33(3):185-8.

[3]. Schellekens GA, et al. The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide. Arthritis Rheum. 2000 Jan;43(1):155-63.

 Chemical & Physical Properties

Molecular Formula C87H145N41O32S2
Molecular Weight 2341.47
Storage condition -20°C
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