PDGFRα/FLT3-ITD-IN-3

Modify Date: 2025-08-25 20:47:55

PDGFRα/FLT3-ITD-IN-3 Structure
PDGFRα/FLT3-ITD-IN-3 structure
Common Name PDGFRα/FLT3-ITD-IN-3
CAS Number 2761259-22-5 Molecular Weight 477.65
Density N/A Boiling Point N/A
Molecular Formula C26H39N9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PDGFRα/FLT3-ITD-IN-3


PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of 0.153 and 0.004 μM, respectively. PDGFRα/FLT3-ITD-IN-3 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].

 Names

Name PDGFRα/FLT3-ITD-IN-3

 PDGFRα/FLT3-ITD-IN-3 Biological Activity

Description PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of 0.153 and 0.004 μM, respectively. PDGFRα/FLT3-ITD-IN-3 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].
Related Catalog
References

[1]. Vlková K, et al. Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors. Bioorg Med Chem Lett. 2022 Mar 15;60:128603

 Chemical & Physical Properties

Molecular Formula C26H39N9
Molecular Weight 477.65
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