2761259-05-4

2761259-05-4 structure

Name: PDGFRα/FLT3-ITD-IN-1
Chemical Name: PDGFRα/FLT3-ITD-IN-1
CAS Number: 2761259-05-4
Molecular Formula: C₂₇H₃₉N₉O
Molecular Weight: 505.66
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FLT3
Create Date: 2022-08-15 18:34:38
Modify Date: 2025-09-28 09:02:39
PDGFRα/FLT3-ITD-IN-1 (Compound 12d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 0.036 and 0.003 μM, respectively. PDGFRα/FLT3-ITD-IN-1 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].

Name	PDGFRα/FLT3-ITD-IN-1

Description	PDGFRα/FLT3-ITD-IN-1 (Compound 12d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 0.036 and 0.003 μM, respectively. PDGFRα/FLT3-ITD-IN-1 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3
References	[1]. Vlková K, et al. Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors. Bioorg Med Chem Lett. 2022 Mar 15;60:128603

Molecular Formula	C₂₇H₃₉N₉O
Molecular Weight	505.66