SOS1-IN-4

Modify Date: 2025-08-20 18:19:20

SOS1-IN-4 Structure
SOS1-IN-4 structure
Common Name SOS1-IN-4
CAS Number 2738392-83-9 Molecular Weight 474.48
Density N/A Boiling Point N/A
Molecular Formula C24H29F2N4O2P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SOS1-IN-4


SOS1-IN-4 is a potent SOS1 inhibitor with an IC50 of 56 nM for KRAS-C12C/SOS1 interaction (WO2021228028 A1, example 65)[1].

 Names

Name SOS1-IN-4

 SOS1-IN-4 Biological Activity

Description SOS1-IN-4 is a potent SOS1 inhibitor with an IC50 of 56 nM for KRAS-C12C/SOS1 interaction (WO2021228028 A1, example 65)[1].
Related Catalog
Target

KRAS-C12C/SOS1:56 nM (IC50)

References

[1]. Sos1 inhibitor containing phosphorus. WO2021228028A1.

 Chemical & Physical Properties

Molecular Formula C24H29F2N4O2P
Molecular Weight 474.48
InChIKey AYUPAZPTYFGDHL-CQSZACIVSA-N
SMILES COc1cc2nc(C)nc(NC(C)c3cc(N)cc(C(F)F)c3)c2cc1P1(=O)CCCCC1
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