SOS1-IN-5

Modify Date: 2025-08-25 20:22:16

SOS1-IN-5 Structure
SOS1-IN-5 structure
Common Name SOS1-IN-5
CAS Number 2716956-47-5 Molecular Weight 536.54
Density N/A Boiling Point N/A
Molecular Formula C26H31F3N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SOS1-IN-5


SOS1-IN-5 is a potent inhibitor of SOS1. SOS1-IN-5 is a pyrimidobicyclic derivative. SOS1-IN-5 blocks the activation of KRAS by interfering with RAS-SOS1 interaction, and achieves the purpose of broad-spectrum inhibition of KRAS activity. SOS1-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2021203768A1, compound 4)[1].

 Names

Name SOS1-IN-5

 SOS1-IN-5 Biological Activity

Description SOS1-IN-5 is a potent inhibitor of SOS1. SOS1-IN-5 is a pyrimidobicyclic derivative. SOS1-IN-5 blocks the activation of KRAS by interfering with RAS-SOS1 interaction, and achieves the purpose of broad-spectrum inhibition of KRAS activity. SOS1-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2021203768A1, compound 4)[1].
Related Catalog
References

[1]. Xin Li, et al. Pyrimidobicyclic derivatives, their preparation method and their application in medicine. Patent WO2021203768A1.

 Chemical & Physical Properties

Molecular Formula C26H31F3N4O5
Molecular Weight 536.54
InChIKey GEZMTRWNCBYKCP-MRXNPFEDSA-N
SMILES Cc1nc(NC(C)c2cc(N)cc(C(F)(F)F)c2)c2cc3c(cc2n1)OCCOCCOCCOCCO3
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