7DG
Modify Date: 2024-01-16 12:19:17
7DG structure
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Common Name | 7DG | ||
|---|---|---|---|---|
| CAS Number | 26927-01-5 | Molecular Weight | 422.51 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H30O5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 7DG7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR; completely protectes macrophages from anthrax lethal toxin (LT)-induced pyroptotic cell death, a model for inflammasome-mediated caspase-1 activation, with an (IC50) of 5 uM. |
| Name | 7DG |
|---|
| Description | 7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR; completely protectes macrophages from anthrax lethal toxin (LT)-induced pyroptotic cell death, a model for inflammasome-mediated caspase-1 activation, with an (IC50) of 5 uM. |
|---|---|
| References | References 1. Hett EC, et al. Nat Chem Biol. 2013 Jun;9(6):398-405. View Related Products by Target Other Targets |
| Molecular Formula | C26H30O5 |
|---|---|
| Molecular Weight | 422.51 |