7DG
Names
[ CAS No. ]:
26927-01-5
[ Name ]:
7DG
Biological Activity
[Description]:
7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR; completely protectes macrophages from anthrax lethal toxin (LT)-induced pyroptotic cell death, a model for inflammasome-mediated caspase-1 activation, with an (IC50) of 5 uM.
[References]
References 1. Hett EC, et al. Nat Chem Biol. 2013 Jun;9(6):398-405. View Related Products by Target Other Targets
Chemical & Physical Properties
[ Molecular Formula ]:
C26H30O5
[ Molecular Weight ]:
422.51
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Hazard Codes ]:
Xn
[ RIDADR ]:
NONH for all modes of transport