7DG

Names

[ Name ]:
7DG

Biological Activity

[Description]:

7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR; completely protectes macrophages from anthrax lethal toxin (LT)-induced pyroptotic cell death, a model for inflammasome-mediated caspase-1 activation, with an (IC50) of 5 uM.

[References]

References 1. Hett EC, et al. Nat Chem Biol. 2013 Jun;9(6):398-405. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₀O₅

[ Molecular Weight ]:
422.51

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.