ADAMTS-5-IN-3
Modify Date: 2025-08-25 16:41:25
ADAMTS-5-IN-3 structure
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Common Name | ADAMTS-5-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 2688733-96-0 | Molecular Weight | 424.32 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H23Cl2N3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ADAMTS-5-IN-3ADAMTS-5-IN-3 (Example 37-2) is a potent inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively. ADAMTS-5-IN-3 can be used for the research of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis[1]. |
| Name | ADAMTS-5-IN-3 |
|---|
| Description | ADAMTS-5-IN-3 (Example 37-2) is a potent inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively. ADAMTS-5-IN-3 can be used for the research of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis[1]. |
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| Related Catalog | |
| References |
[1]. Dong Liu, et al. Adamts inhibitors, preparation methods and medicinal uses thereof. WO2021158626A1. |
| Molecular Formula | C20H23Cl2N3O3 |
|---|---|
| Molecular Weight | 424.32 |