2688733-96-0
2688733-96-0 structure
- Name: ADAMTS-5-IN-3
- Chemical Name: ADAMTS-5-IN-3
- CAS Number: 2688733-96-0
- Molecular Formula: C20H23Cl2N3O3
- Molecular Weight: 424.32
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2022-04-06 15:02:31
- Modify Date: 2025-08-25 16:41:25
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ADAMTS-5-IN-3 (Example 37-2) is a potent inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively. ADAMTS-5-IN-3 can be used for the research of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis[1].
| Name | ADAMTS-5-IN-3 |
|---|
| Description | ADAMTS-5-IN-3 (Example 37-2) is a potent inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively. ADAMTS-5-IN-3 can be used for the research of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis[1]. |
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| Related Catalog | |
| References |
[1]. Dong Liu, et al. Adamts inhibitors, preparation methods and medicinal uses thereof. WO2021158626A1. |
| Molecular Formula | C20H23Cl2N3O3 |
|---|---|
| Molecular Weight | 424.32 |