FD2056

Modify Date: 2024-08-09 19:56:35

FD2056 structure	Common Name	FD2056
	CAS Number	2685870-87-3	Molecular Weight	476.94
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₁₇ClN₆O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FD2056

FD2056 is a potent and orally active PI3K inhibitor. FD2056 inhibits PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ with IC50s of 0.30, 0.80, 1.10, 0.42 nM. FD2056 also inhibits CDK2-CyclinA2 and CDK4-CyclinD3 with IC50 of 115.95 and 2782.15 nM. FD2056 inhibits breast cancer cell proliferation with IC50s of 1.06, 0.04, 1.40 μM for MDA-MB-231, MDA-MB-468, MCF-7 cells. FD2056 also induces cancer apoptosis and inhibits tumor growth[1].

Name	FD2056

Description	FD2056 is a potent and orally active PI3K inhibitor. FD2056 inhibits PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ with IC50s of 0.30, 0.80, 1.10, 0.42 nM. FD2056 also inhibits CDK2-CyclinA2 and CDK4-CyclinD3 with IC50 of 115.95 and 2782.15 nM. FD2056 inhibits breast cancer cell proliferation with IC50s of 1.06, 0.04, 1.40 μM for MDA-MB-231, MDA-MB-468, MCF-7 cells. FD2056 also induces cancer apoptosis and inhibits tumor growth[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K
References	[1]. Yang C, et al. Discovery and identification of a novel PI3K inhibitor with enhanced CDK2 inhibition for the treatment of triple negative breast cancer. Bioorg Chem. 2023 Aug 9;140:106779.

Molecular Formula	C₂₃H₁₇ClN₆O₂S
Molecular Weight	476.94

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
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Purity: 98.0%
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FD2056

Use of FD2056

Names

FD2056 Biological Activity

Chemical & Physical Properties