2685870-87-3
2685870-87-3 structure
- Name: FD2056
- Chemical Name: FD2056
- CAS Number: 2685870-87-3
- Molecular Formula: C23H17ClN6O2S
- Molecular Weight: 476.94
- Catalog: Signaling Pathways PI3K/Akt/mTOR PI3K
- Create Date: 2024-08-09 19:56:35
- Modify Date: 2024-08-09 19:56:35
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FD2056 is a potent and orally active PI3K inhibitor. FD2056 inhibits PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ with IC50s of 0.30, 0.80, 1.10, 0.42 nM. FD2056 also inhibits CDK2-CyclinA2 and CDK4-CyclinD3 with IC50 of 115.95 and 2782.15 nM. FD2056 inhibits breast cancer cell proliferation with IC50s of 1.06, 0.04, 1.40 μM for MDA-MB-231, MDA-MB-468, MCF-7 cells. FD2056 also induces cancer apoptosis and inhibits tumor growth[1].
| Name | FD2056 |
|---|
| Description | FD2056 is a potent and orally active PI3K inhibitor. FD2056 inhibits PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ with IC50s of 0.30, 0.80, 1.10, 0.42 nM. FD2056 also inhibits CDK2-CyclinA2 and CDK4-CyclinD3 with IC50 of 115.95 and 2782.15 nM. FD2056 inhibits breast cancer cell proliferation with IC50s of 1.06, 0.04, 1.40 μM for MDA-MB-231, MDA-MB-468, MCF-7 cells. FD2056 also induces cancer apoptosis and inhibits tumor growth[1]. |
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| Molecular Formula | C23H17ClN6O2S |
|---|---|
| Molecular Weight | 476.94 |