PPARγ-IN-2

Modify Date: 2024-01-10 13:16:43

PPARγ-IN-2 structure	Common Name	PPARγ-IN-2
	CAS Number	2682078-97-1	Molecular Weight	335.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₁N₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PPARγ-IN-2

PPARγ-IN-2 (Compound 5a) is a PPARγ inhibitor. PPARγ-IN-2 inhibits TG accumulation in 3T3-L1 preadipocytes (EC50: 0.106 μM). PPARγ-IN-2 inhibits high-cholesterol diet (HFC)-induced obesity and related metabolic syndrome, and reduces lipid accumulation in adipose tissue[1].

Name	PPARγ-IN-2

Description	PPARγ-IN-2 (Compound 5a) is a PPARγ inhibitor. PPARγ-IN-2 inhibits TG accumulation in 3T3-L1 preadipocytes (EC50: 0.106 μM). PPARγ-IN-2 inhibits high-cholesterol diet (HFC)-induced obesity and related metabolic syndrome, and reduces lipid accumulation in adipose tissue[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Metabolic Disease
Target	PPARγ
References	[1]. Guo SY, et al. Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism. Eur J Med Chem. 2023 Nov 15;260:115729.

Molecular Formula	C₁₉H₂₁N₅O
Molecular Weight	335.40

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PPARγ-IN-2

Use of PPARγ-IN-2

Names

PPARγ-IN-2 Biological Activity

Chemical & Physical Properties