2682078-97-1

2682078-97-1 structure

Name: PPARγ-IN-2
Chemical Name: PPARγ-IN-2
CAS Number: 2682078-97-1
Molecular Formula: C₁₉H₂₁N₅O
Molecular Weight: 335.40
Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
Create Date: 2023-11-04 13:06:03
Modify Date: 2025-10-03 15:20:59
PPARγ-IN-2 (Compound 5a) is a PPARγ inhibitor. PPARγ-IN-2 inhibits TG accumulation in 3T3-L1 preadipocytes (EC50: 0.106 μM). PPARγ-IN-2 inhibits high-cholesterol diet (HFC)-induced obesity and related metabolic syndrome, and reduces lipid accumulation in adipose tissue[1].

Name	PPARγ-IN-2

Description	PPARγ-IN-2 (Compound 5a) is a PPARγ inhibitor. PPARγ-IN-2 inhibits TG accumulation in 3T3-L1 preadipocytes (EC50: 0.106 μM). PPARγ-IN-2 inhibits high-cholesterol diet (HFC)-induced obesity and related metabolic syndrome, and reduces lipid accumulation in adipose tissue[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Metabolic Disease
Target	PPARγ
References	[1]. Guo SY, et al. Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism. Eur J Med Chem. 2023 Nov 15;260:115729.

Molecular Formula	C₁₉H₂₁N₅O
Molecular Weight	335.40