ZDWX-25

Modify Date: 2025-08-21 15:39:53

ZDWX-25 Structure
ZDWX-25 structure
 Common Name ZDWX-25
CAS Number 2668297-70-7 Molecular Weight 309.32
Density N/A Boiling Point N/A
Molecular Formula C17H15N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ZDWX-25


ZDWX-25 is a highly potent GSK-3β and DYRK1A dual inhibitor with an IC50 value of 71 nM for GSK-3β. ZDWX-25 possesses significant cytotoxic activities against SH-SY5Y and HL-7702 cells. ZDWX-25 can be used for researching alzheimer's disease[1].

 Names

Name ZDWX-25

 ZDWX-25 Biological Activity

Description ZDWX-25 is a highly potent GSK-3β and DYRK1A dual inhibitor with an IC50 value of 71 nM for GSK-3β. ZDWX-25 possesses significant cytotoxic activities against SH-SY5Y and HL-7702 cells. ZDWX-25 can be used for researching alzheimer's disease[1].
Related Catalog
Target

GSK-3β:71 nM (IC50)

References

[1]. Liu W, et al. Discovery of novel β-carboline derivatives as selective AChE inhibitors with GSK-3β inhibitory property for the treatment of Alzheimer's disease. Eur J Med Chem. 2022;229:114095.

 Chemical & Physical Properties

Molecular Formula C17H15N3O3
Molecular Weight 309.32
InChIKey HYXRYQYCRBSSIY-UHFFFAOYSA-N
SMILES COC(=O)c1ccc2c(c1)[nH]c1c(NC(=O)C3CC3)cccc12
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Chemsrc provides ZDWX-25(CAS#:2668297-70-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of ZDWX-25 are included as well.>> amp version: ZDWX-25

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