1-Vinyl-4-methoxy-β-carboline

Modify Date: 2024-02-15 12:34:09

1-Vinyl-4-methoxy-β-carboline Structure
1-Vinyl-4-methoxy-β-carboline structure
Common Name 1-Vinyl-4-methoxy-β-carboline
CAS Number 26585-13-7 Molecular Weight 224.258
Density 1.3±0.1 g/cm3 Boiling Point 461.2±40.0 °C at 760 mmHg
Molecular Formula C14H12N2O Melting Point N/A
MSDS N/A Flash Point 151.1±17.0 °C

 Use of 1-Vinyl-4-methoxy-β-carboline


Dehydrocrenatidine, a β-carboline alkaloid that can be isolated from Picrasma quassioides. Dehydrocrenatidine induces cell Apoptosis by activates ERK and JNK. Dehydrocrenatidine inhibits invasion and migration of cancer cells, it also suppresses neuronal excitability to exert analgesic effects[1][2].

 Names

Name 1-ethenyl-4-methoxy-9H-pyrido[3,4-b]indole
Synonym More Synonyms

 1-Vinyl-4-methoxy-β-carboline Biological Activity

Description Dehydrocrenatidine, a β-carboline alkaloid that can be isolated from Picrasma quassioides. Dehydrocrenatidine induces cell Apoptosis by activates ERK and JNK. Dehydrocrenatidine inhibits invasion and migration of cancer cells, it also suppresses neuronal excitability to exert analgesic effects[1][2].
Related Catalog
References

[1]. Ho HY, et al. Apoptotic effects of dehydrocrenatidine via JNK and ERK pathway regulation in oral squamous cell carcinoma. Biomed Pharmacother. 2021 May;137:111362.  

[2]. Hsieh MC, et al. Dehydrocrenatidine extracted from Picrasma quassioidesinduces the apoptosis of nasopharyngeal carcinoma cells through the JNK and ERK signaling pathways. Oncol Rep. 2021 Aug;46(2):166.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 461.2±40.0 °C at 760 mmHg
Molecular Formula C14H12N2O
Molecular Weight 224.258
Flash Point 151.1±17.0 °C
Exact Mass 224.094955
PSA 37.91000
LogP 3.79
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.737

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1-Vinyl-4-methoxy-β-carboline
9H-Pyrido[3,4-b]indole, 1-ethenyl-4-methoxy-
dehydrocrenatine
HMS2271N07
TOB-10
Dehydrocrenation
4-Methoxy-1-vinyl-9H-β-carboline