26585-13-7

26585-13-7 structure

Name: 1-Vinyl-4-methoxy-β-carboline
Chemical Name: 1-ethenyl-4-methoxy-9H-pyrido[3,4-b]indole
CAS Number: 26585-13-7
Molecular Formula: C₁₄H₁₂N₂O
Molecular Weight: 224.258
Catalog: Natural product Alkaloid
Create Date: 2017-03-31 23:05:14
Modify Date: 2024-02-15 12:34:09
Dehydrocrenatidine, a β-carboline alkaloid that can be isolated from Picrasma quassioides. Dehydrocrenatidine induces cell Apoptosis by activates ERK and JNK. Dehydrocrenatidine inhibits invasion and migration of cancer cells, it also suppresses neuronal excitability to exert analgesic effects[1][2].

Name	1-ethenyl-4-methoxy-9H-pyrido[3,4-b]indole
Synonyms	1-Vinyl-4-methoxy-β-carboline 9H-Pyrido[3,4-b]indole, 1-ethenyl-4-methoxy- dehydrocrenatine HMS2271N07 TOB-10 Dehydrocrenation 4-Methoxy-1-vinyl-9H-β-carboline

Description	Dehydrocrenatidine, a β-carboline alkaloid that can be isolated from Picrasma quassioides. Dehydrocrenatidine induces cell Apoptosis by activates ERK and JNK. Dehydrocrenatidine inhibits invasion and migration of cancer cells, it also suppresses neuronal excitability to exert analgesic effects[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> MAPK/ERK Pathway >> ERK Research Areas >> Neurological Disease Signaling Pathways >> MAPK/ERK Pathway >> JNK Signaling Pathways >> Stem Cell/Wnt >> ERK
References	[1]. Ho HY, et al. Apoptotic effects of dehydrocrenatidine via JNK and ERK pathway regulation in oral squamous cell carcinoma. Biomed Pharmacother. 2021 May;137:111362. [2]. Hsieh MC, et al. Dehydrocrenatidine extracted from Picrasma quassioidesinduces the apoptosis of nasopharyngeal carcinoma cells through the JNK and ERK signaling pathways. Oncol Rep. 2021 Aug;46(2):166.

Hazard Codes	Xi
HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%