BRG1-IN-1

Modify Date: 2025-08-31 17:20:53

BRG1-IN-1 structure	Common Name	BRG1-IN-1
	CAS Number	2616813-99-9	Molecular Weight	322.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₉FN₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BRG1-IN-1

BRG1-IN-1 (Compound 11d) is a potent inhibitor of BRG1. BRG1-IN-1 shows better efficacy than PFI-3 in sensitizing GBM cells to the antiproliferative and cell death inducing effects of Temozolomide in vitro. BRG1-IN-1 enhances the inhibitor effect of Temozolomide on the growth of subcutaneous GBM tumors[1].

Name	BRG1-IN-1

Description	BRG1-IN-1 (Compound 11d) is a potent inhibitor of BRG1. BRG1-IN-1 shows better efficacy than PFI-3 in sensitizing GBM cells to the antiproliferative and cell death inducing effects of Temozolomide in vitro. BRG1-IN-1 enhances the inhibitor effect of Temozolomide on the growth of subcutaneous GBM tumors[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. He Y, et al. Novel structural-related analogs of PFI-3 (SRAPs) that target the BRG1 catalytic subunit of the SWI/SNF complex increase the activity of temozolomide in glioblastoma cells. Bioorg Med Chem. 2022 Jan 1;53:116533.

Molecular Formula	C₂₀H₁₉FN₂O
Molecular Weight	322.38

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BRG1-IN-1

Use of BRG1-IN-1

Names

BRG1-IN-1 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.