Frentizole

Modify Date: 2025-08-27 14:04:00

Use of Frentizole

Frentizole, an FDA-approved immunosuppressive drug, is a novel inhibitor of the Aβ-ABAD interaction.IC50 value:Target: Aβ-ABAD interaction

Name	1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenylurea
Synonym	More Synonyms

Description	Frentizole, an FDA-approved immunosuppressive drug, is a novel inhibitor of the Aβ-ABAD interaction.IC50 value:Target: Aβ-ABAD interaction
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Amyloid-β Research Areas >> Inflammation/Immunology
References	[1]. I I Scheetz ME, D G Carlson, and M R Schinitsky Frentizole, a novel immunosuppressive, and azathioprine: their comparative effects on host resistance to Pseudomonas aeruginosa, Candida albicans, herpes simplex virus, and influenza (Ann Arbor) virus. Infec [2]. Hatfield SM, Hartley LW, Schmidtke JR. The immunomodulatory action of frentizole, a novel immunosuppressive agent. Immunopharmacology. 1982 Dec;5(2):169-79. [3]. Xie, Yuli; Deng, Shixian; Chen, Zhenzhang et al. Identification of small-molecule inhibitors of the Aβ-ABAD interaction. Bioorganic & Medicinal Chemistry Letters (2006), 16(17), 4657-4660.

Description

Frentizole, an FDA-approved immunosuppressive drug, is a novel inhibitor of the Aβ-ABAD interaction.IC50 value:Target: Aβ-ABAD interaction

Related Catalog

Signaling Pathways >> Neuronal Signaling >> Amyloid-β

Research Areas >> Inflammation/Immunology

References

Density	1.42g/cm3
Molecular Formula	C₁₅H₁₃N₃O₂S
Molecular Weight	299.34800
Exact Mass	299.07300
PSA	94.98000
LogP	4.03550
Index of Refraction	1.752
InChIKey	JHBWYQRKOUBPCA-UHFFFAOYSA-N
SMILES	COc1ccc2nc(NC(=O)Nc3ccccc3)sc2c1
Storage condition	2-8℃

HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

FRENTIZOLE

1-(6-methoxybenzo[d]thiazol-2-yl)-3-phenylurea

1-(6-methoxy-2-benzothiazolyl)-3-phenylurea

Frentizol

1-(6-methoxy-benzothiazol-2-yl)-3-phenyl-urea

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Price: $145/10mM*1mLinDMSO

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