Cambendazol

Modify Date: 2025-08-25 16:49:08

Cambendazol structure	Common Name	Cambendazol
	CAS Number	26097-80-3	Molecular Weight	302.352
	Density	1.4±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₄N₄O₂S	Melting Point	212-214℃ (ethyl acetate hexane )
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS08	Signal Word	Warning

Use of Cambendazol

Cambendazole is one of the most effective agents for the therapy of human strongyloidiasis and [1].

Name	propan-2-yl N-[2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-yl]carbamate
Synonym	More Synonyms

Description	Cambendazole is one of the most effective agents for the therapy of human strongyloidiasis and [1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Bicalho SA, et al. Cambendazole in the treatment of human strongyloidiasis. Am J Trop Med Hyg. 1983 Sep;32(5):1181-3.

Density	1.4±0.1 g/cm3
Melting Point	212-214℃ (ethyl acetate hexane )
Molecular Formula	C₁₄H₁₄N₄O₂S
Molecular Weight	302.352
Exact Mass	302.083740
PSA	108.14000
LogP	2.90
Index of Refraction	1.694
InChIKey	QZWHWHNCPFEXLL-UHFFFAOYSA-N
SMILES	CC(C)OC(=O)Nc1ccc2nc(-c3cscn3)[nH]c2c1

Cambendazol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DD6538000

CHEMICAL NAME :: 5-Benzimidazolecarbamic acid, 2-(4-thiazolyl)-, isopropyl ester

CAS REGISTRY NUMBER :: 26097-80-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C14-H14-N4-O2-S

MOLECULAR WEIGHT :: 302.38

WISWESSER LINE NOTATION :: T56 BM DNJ GMVOY1&1 C- ET5N CSJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 80480 ug/kg

SEX/DURATION :: female 8-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 60400 ug/kg

SEX/DURATION :: female 8-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 60800 ug/kg

SEX/DURATION :: female 8-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 80800 ug/kg

SEX/DURATION :: female 8-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 348 mg/kg

SEX/DURATION :: female 6-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 348 mg/kg

SEX/DURATION :: female 6-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 75 mg/kg

SEX/DURATION :: female 21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - urogenital system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 75 mg/kg

SEX/DURATION :: female 21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Mammal - domestic Leukocyte

DOSE/DURATION :: 1 mg/L

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 31,505,1976

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H361
Precautionary Statements	P281
Hazard Codes	Xn
Risk Phrases	63
Safety Phrases	36/37
RIDADR	NONH for all modes of transport
RTECS	DD6538000

2-thiazol-4-yl-...

CAS#:25893-06-5

Isopropyl chlor...

CAS#:108-23-6

Cambendazol

CAS#:26097-80-3

Literature: Merck and Co., Inc. Patent: US3956488 A1, 1976 ;

2-Nitro-1,4-ben...

CAS#:5307-14-2

Cambendazol

CAS#:26097-80-3

Literature: Rajappa, S.; Sreenivasan, R. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 7 p. 539 - 541

4-isopropoxycar...

CAS#:30713-39-4

Cambendazol

CAS#:26097-80-3

Literature: Rajappa, S.; Sreenivasan, R. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 7 p. 539 - 541

Thiazole-4-carb...

CAS#:3364-80-5

N/A

CAS#:35198-67-5

Cambendazol

CAS#:26097-80-3

Literature: Rajappa, S.; Sreenivasan, R. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 7 p. 539 - 541

Precursor 4
CAS#:108-23-6 Isopropyl chlor... CAS#:5307-14-2 2-Nitro-1,4-ben... CAS#:30713-39-4 4-isopropoxycar... CAS#:3364-80-5 Thiazole-4-carb...
DownStream 0

The Hymenolepis diminuta-golden hamster (Mesocricetus auratus) model for the evaluation of gastrointestinal anticestode activity.

J. Parasitol. 90(4) , 898-9, (2004)

A novel laboratory anticestode assay was developed using Hymenolepis diminuta in the hamster. The commercial anticestode compounds, praziquantel, bunamidine, and niclosamide were active against patent...

Structural requirements for the induction of cytochromes P450 by benzimidazole anthelmintic derivatives in cultured rabbit hepatocytes.

Biochem. Biophys. Res. Commun. 220(3) , 789-94, (1996)

The effect of sulfur-containing benzimidazoles (thiabendazole, 5-hydroxy-thiabendazole, cambendazole) and sulfur-free derivatives (benzimidazole, carbendazim and 5-hydroxycarbendazim) on cytochrome P4...

Controlled tests of activity of several antiparasitic compounds against natural infections of Haemonchus contortus and other helminths in lambs from a flock established in 1962.

Am. J. Vet. Res. 54(3) , 406-10, (1993)

Antiparasitic activity of several compounds was evaluated over a long period (about 25 years) in the same flock of sheep. Haemonchus contortus was of special interest, including its relation to drug r...

Cambenzole

Carbamic acid, N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]-, 1-methylethyl ester

Novazole

Isopropyl [2-(1,3-thiazol-4-yl)-1H-benzimidazol-5-yl]carbamate

Equiben

Camvet

(2-thiazol-4-yl-1(3)H-benzoimidazol-5-yl)-carbamic acid isopropyl ester

CBDZ

propan-2-yl [2-(1,3-thiazol-4-yl)-1H-benzimidazol-5-yl]carbamate

cambendazole

Carbamic acid, (2-(4-thiazolyl)-1H-benzimidazol-5-yl)-, 1-methylethyl ester

Isopropyl 2-(4-thiazolyl)-5-benzimidazolecarbamate

NOE [French]

Noviben

Bonlam

[2-(4-thiazolyl)-1H-benzimidazol-5-yl]carbamic acid 1-methylethyl ester

5-isopropoxycarbonylamino-2-(4'-thiazolyl)-benzimidazole

Camdan

Cambendazol

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China
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Cambendazole
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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