2-Nitro-1,4-benzenediamine

Modify Date: 2025-08-22 22:06:31

2-Nitro-1,4-benzenediamine structure	Common Name	2-Nitro-1,4-benzenediamine
	CAS Number	5307-14-2	Molecular Weight	153.139
	Density	1.4±0.1 g/cm3	Boiling Point	385.4±22.0 °C at 760 mmHg
	Molecular Formula	C₆H₇N₃O₂	Melting Point	135-138 °C(lit.)
	MSDS	Chinese USA	Flash Point	186.9±22.3 °C
	Symbol	GHS07	Signal Word	Warning

Name	2-nitro-p-phenylenediamine
Synonym	More Synonyms

Density	1.4±0.1 g/cm3
Boiling Point	385.4±22.0 °C at 760 mmHg
Melting Point	135-138 °C(lit.)
Molecular Formula	C₆H₇N₃O₂
Molecular Weight	153.139
Flash Point	186.9±22.3 °C
Exact Mass	153.053833
PSA	97.86000
LogP	0.91
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.708
Stability	Stable. Incompatible with strong oxidizing agents.
Water Solubility	<0.1 g/100 mL at 22 ºC

2-Nitro-1,4-benzenediamine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ST3000000

CHEMICAL NAME :: p-Phenylenediamine, 2-nitro-

CAS REGISTRY NUMBER :: 5307-14-2

BEILSTEIN REFERENCE NO. :: 2210195

LAST UPDATED :: 199710

DATA ITEMS CITED :: 54

MOLECULAR FORMULA :: C6-H7-N3-O2

MOLECULAR WEIGHT :: 153.16

WISWESSER LINE NOTATION :: ZR DZ BNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2100 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 348 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 214 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 288 gm/kg/78W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 144 gm/kg/78W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 1600 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 1600 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 2240 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - eye/ear

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 1280 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TEST SYSTEM :: Rodent - hamster

DOSE/DURATION :: 125 mg/kg

REFERENCE :: BLFSBY Basic Life Sciences. (Plenum Pub. Corp., 223 Spring St., New York, NY 10003) V.1- 1973- Volume(issue)/page/year: 29B,613,1984 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,185,1993 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,73,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,73,1978 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,185,1993 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,185,1993 TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(3),161,1985 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Skin;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1644 No. of Facilities: 3160 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 29422 (estimated) No. of Female Employees: 23531 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H317
Precautionary Statements	P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R68
Safety Phrases	S36/37-S45
RIDADR	3143
WGK Germany	2
RTECS	ST3000000
Packaging Group	I; II; III
Hazard Class	6.1
HS Code	29215119

Precursor 9
CAS#:97-02-9 2,4-Dinitroaniline CAS#:2871-01-4 2-[(4-Amino-2-n... CAS#:7418-43-1 4-Amino-2-nitro... CAS#:106-50-3 p-Phenylenediamine
CAS#:5345-53-9 1,4-Diacetamino... CAS#:122-80-5 4'-Aminoacetanilide CAS#:6086-29-9 1-N-ACETYL-3-NI... CAS#:33672-95-6 ethyl 2,4-dinit...
CAS#:84228-46-6 Ethyl 4-amino-2...
DownStream 10
CAS#:491871-67-1 N4-(4-Fluoroben... CAS#:150812-23-0 Ethyl {4-[(4-fl... CAS#:27173-95-1 Benzenesulfonam... CAS#:25826-33-9 N-(4-acetamido-...
CAS#:6086-29-9 1-N-ACETYL-3-NI... CAS#:119-34-6 2-nitro-4-amino... CAS#:150812-12-7 Retigabine CAS#:16383-62-3 2,5-Cyclohexadi...
CAS#:150812-21-8 2-Amino-5-[(4-f... CAS#:21784-73-6 4-Iodo-2-nitrophenol

HS Code	2921519090
Summary	2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%

Teratogenic evaluation of 2-nitro-p-phenylenediamine, 4-nitro-o-phenylenediamine, and 2,5-toluenediamine sulfate in the mouse.

Teratology 24(3) , 253-65, (1981)

Pregnant outbred albino (CD-1) mice were given 2-nitro-p-phenylenediamine (2NPPD; 32-256 mg/kg/day), 4-nitro-o-phenylenediamine (4NOPD; 16-1024 mg/kg/day) or 2,5-toluenediamine sulfate (2,5TDS; 16-64 ...

Metabolism of the hair dye component, nitro-p-phenylenediamine, in the rat.

Chem. Pharm. Bull. 35(2) , 785-91, (1987)

Regioselective N-acetylation as a route of nitro-9-phenylenediamine metabolism by rat liver cytosol.

Chem. Pharm. Bull. 38(9) , 2561-6, (1990)

Regioselectivity in N-acetylation of nitro-0-phenylenediamine, a widely used hair dye component, by rat liver cytosolic N-acetyltransferases was studied in relation to its substituent effects on enzym...

2-NPPD

2-Nitro-p-phenylenediamine

2-Nitro-1,4-phenylenediaMine

dyegs

2-nitrobenzene-1,4-diamine

2NDB

1,4-Diamino-2-nitrobenzene

2,5-diamino-nitrobenzene

2-N-p-PDA

1,4-diamino-nitrobenzene

2-nitro-1,4-diamino-benzene

MFCD00007903

2-Nitro-1,4-benzenediamine

1,4-Benzenediamine, 2-nitro-

NITRO-PPD

Rodol 2R

EINECS 226-164-5

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-Nitro-1,4-benzenediamine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 2-Nitro-1,4-benzenediamine
Price: ￥228.0/100g ￥78.0/25g
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,4-Diamino-2-nitrobenzene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2-Nitro-1,4-phenylenediamine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

2-Nitro-1,4-benzenediamine suppliers

2-Nitro-1,4-benzenediamine price

2-Nitro-1,4-benzenediamine

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles18

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.