2-nitro-4-aminophenol
2-nitro-4-aminophenol structure
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Common Name | 2-nitro-4-aminophenol | ||
|---|---|---|---|---|
| CAS Number | 119-34-6 | Molecular Weight | 154.123 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 334.5±27.0 °C at 760 mmHg | |
| Molecular Formula | C6H6N2O3 | Melting Point | 125-127 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 156.1±23.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Summary: 4-Amino-2-nitrophenol, also known as 2-nitro-4-aminophenol (CAS number: 119-34-6), has a molecular formula of C6H6N2O3 and a molecular weight of 154.123. It appears as a dark brown crystalline powder with a melting point of 125-127 °C. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-Amino-2-nitrophenol |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 334.5±27.0 °C at 760 mmHg |
| Melting Point | 125-127 °C(lit.) |
| Molecular Formula | C6H6N2O3 |
| Molecular Weight | 154.123 |
| Flash Point | 156.1±23.7 °C |
| Exact Mass | 154.037842 |
| PSA | 92.07000 |
| LogP | 0.64 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.689 |
| InChIKey | WHODQVWERNSQEO-UHFFFAOYSA-N |
| SMILES | Nc1ccc(O)c([N+](=O)[O-])c1 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S22-S24/25-S37/39-S26 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | SJ6303000 |
| Hazard Class | 6.1 |
| HS Code | 2922299090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 6 | |
CAS#:123-30-8
CAS#:51-28-5![2-[(4-Amino-2-nitrophenyl)amino]ethanol Structure](https://image.chemsrc.com/caspic/065/2871-01-4.png)
CAS#:2871-01-4
CAS#:5307-14-2
CAS#:364-76-1
CAS#:635-22-3
CAS#:19077-69-1
CAS#:67329-17-3
CAS#:51288-37-0
CAS#:51642-26-3
CAS#:394-33-2
CAS#:577-72-0![N-[[4-(5-iodopyrimidin-2-yl)oxy-3-nitrophenyl]carbamoyl]-2-nitrobenzamide structure](https://image.chemsrc.com/caspic/335/103828-99-5.png)
CAS#:103828-99-5
CAS#:21784-73-6This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2922299090 |
|---|---|
| Summary | 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Percutaneous absorption of nitroaromatic compounds: in vivo and in vitro studies in the human and monkey.
J. Invest. Dermatol. 84(3) , 180-3, (1985) The percutaneous absorption of 2-nitro-p-phenylene-diamine, 4-amino-2-nitrophenol, nitrobenzene, p-nitroaniline, and 2,4-dinitrochlorobenzene was measured through human and monkey skin. Human studies ... |
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Plasma levels and kinetic disposition of 2,4-dinitrophenol and its metabolites 2-amino-4-nitrophenol and 4-amino-2-nitrophenol in the mouse.
J. Chromatogr. A. 344 , 177-86, (1985) Eleven groups of six ICR mice were dosed orally with 22.5 mg/kg 2,4-dinitrophenol. Groups were sacrificed at 0, 0.5, 1, 2, 4, 6, 9, 12, 24, 48, and 96 h post-treatment and plasma was collected for ana... |
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The nonmutagenicity of purified 4-amino-2-nitrophenol in Salmonella typhimurium.
Carcinogenesis 3(7) , 809-13, (1982) Two samples of 4-amino-2-nitrophenol were tested for mutagenicity in Salmonella typhimurium strains TA1535, TA1537, TA1538, TA98, and TA100. Significant mutagenic activity was detected with a sample o... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600
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Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958
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Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2-hydroxy-5-aminonitrobenzene |
| 5-amino-2-hydroxynitrobenzene |
| 4-hydroxy-3-nitroaniline |
| 4-Amino-2-nitrophenol |
| cioxidationbase25 |
| 2-nitro-4-aminophenol |
| fourrinebrownpr |
| fourrinebrownpropyl |
| EINECS 204-316-1 |
| MFCD00007876 |
| fourrine57 |
| oxidationbase25 |
| 4-hydroxy-3-nitrobenzenamine |
| 4-NH2-2-NO2-phenol |
| Aminonitrophenol |
| 2-nitro-p-aminophenol |
| 4-amino-2-nitrofenol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the upstream materials of 4-Amino-2-nitrophenol? |
| A: Related upstream materials(CAS) of 4-Amino-2-nitrophenol: 123-30-8;51-28-5;2871-01-4;5307-14-2;364-76-1;635-22-3;19077-69-1;67329-17-3;51288-37-0;51642-26-3. |
| Q: What is the molecular weight of 4-Amino-2-nitrophenol? |
| A: Molecular weight of 4-Amino-2-nitrophenol is 154.123. |
| Q: What is the boiling point of 4-Amino-2-nitrophenol? |
| A: Boiling point of 4-Amino-2-nitrophenol is 334.5±27.0 °C at 760 mmHg. |
| Q: What is the molecular formula of 4-Amino-2-nitrophenol? |
| A: Molecular formula of 4-Amino-2-nitrophenol is C6H6N2O3. |
| Q: What is the melting point of 4-Amino-2-nitrophenol? |
| A: Melting point of 4-Amino-2-nitrophenol is 125-127 °C(lit.). |
| Q: What is the safety information for 4-Amino-2-nitrophenol? |
| A: Safety information for 4-Amino-2-nitrophenol: S22-S24/25-S37/39-S26. |
| Q: What is the InChIKey of 4-Amino-2-nitrophenol? |
| A: InChIKey of 4-Amino-2-nitrophenol is WHODQVWERNSQEO-UHFFFAOYSA-N. |
| Q: What is the polar surface area (PSA) of 4-Amino-2-nitrophenol? |
| A: Polar surface area (PSA) of 4-Amino-2-nitrophenol is 92.07000. |
| Q: What are the downstream products of 4-Amino-2-nitrophenol? |
| A: Related downstream products(CAS) of 4-Amino-2-nitrophenol: 394-33-2;577-72-0;103828-99-5;21784-73-6;51288-37-0;51642-26-3. |
| Q: What is the SMILES notation of 4-Amino-2-nitrophenol? |
| A: SMILES notation of 4-Amino-2-nitrophenol is Nc1ccc(O)c([N+](=O)[O-])c1. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |