Funalenone

Modify Date: 2025-08-24 23:48:26

Funalenone structure	Common Name	Funalenone
	CAS Number	259728-61-5	Molecular Weight	288.25
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₂O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Funalenone

Funalenone (BMS-304245) is a MraY + MurG inhibitor with an IC50 of 25.5 μM in a MraY + MurG membrane plate assay. Funalenone inhibits Staphylococcus aureus (A15090) with an MIC of 64 μg/mL. Funalenone also inhibits MMP-1 with an IC50 of 170 μM[1][2].

Name	4,6,7,9-tetrahydroxy-8-methoxy-3-methylphenalen-1-one
Synonym	More Synonyms

Description	Funalenone (BMS-304245) is a MraY + MurG inhibitor with an IC50 of 25.5 μM in a MraY + MurG membrane plate assay. Funalenone inhibits Staphylococcus aureus (A15090) with an MIC of 64 μg/mL. Funalenone also inhibits MMP-1 with an IC50 of 170 μM[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> MMP Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Integrase Signaling Pathways >> Anti-infection >> Bacterial
Target	collagenases 1 HIV Integrase:10 μM (IC50)
References	[1]. J Inokoshi, et al. Funalenone, a novel collagenase inhibitor produced by Aspergillus niger. J Antibiot (Tokyo). 1999 Dec;52(12):1095-100. [2]. Zawadzke LE, et al. Targeting the MraY and MurG bacterial enzymes for antimicrobial therapeutic intervention. Anal Biochem. 2003 Mar 15;314(2):243-52. [3]. Kazuro Shiomi, et al. Fungal phenalenones inhibit HIV-1 integrase. J Antibiot (Tokyo). 2005 Jan;58(1):65-8. [4]. Inokoshi J, et al. Funalenone, a novel collagenase inhibitor produced by Aspergillus niger. J Antibiot (Tokyo). 1999 Dec;52(12):1095-100.

Molecular Formula	C₁₅H₁₂O₆
Molecular Weight	288.25
Exact Mass	288.06300
PSA	107.22000
LogP	2.27040

8-deoxyxanthoherquein

Funalenone

1H-Phenalen-1-one,3,4,7,9-tetrahydroxy-2-methoxy-6-methyl

3,4,7,9-tetrahydroxy-2-methoxy-6-methyl-1H-phenalen-1-one

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Funalenone
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Purity: 98.0%
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Funalenone

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.