Spermine Prodrug-1

Modify Date: 2025-09-11 18:33:01

Spermine Prodrug-1 Structure
Spermine Prodrug-1 structure
 Common Name Spermine Prodrug-1
CAS Number 2576358-68-2 Molecular Weight 576.00
Density N/A Boiling Point N/A
Molecular Formula C24H45Cl3N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Spermine Prodrug-1


Spermine Prodrug-1 (Compound 1) is a redox-sensitive spermine prodrug for the potential treatment of snyder robinson syndrome. Spermine Prodrug-1 inhibits wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, and CMS-6233) fibroblast cells with IC50s of 326.7, 198.5, and 244.1 μM, respectively[1].

 Names

Name Spermine Prodrug-1

 Spermine Prodrug-1 Biological Activity

Description Spermine Prodrug-1 (Compound 1) is a redox-sensitive spermine prodrug for the potential treatment of snyder robinson syndrome. Spermine Prodrug-1 inhibits wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, and CMS-6233) fibroblast cells with IC50s of 326.7, 198.5, and 244.1 μM, respectively[1].
Related Catalog
References

[1]. Mukund P Tantak, et al. Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome. J Med Chem. 2021 Nov 11;64(21):15593-15607.

 Chemical & Physical Properties

Molecular Formula C24H45Cl3N4O5
Molecular Weight 576.00
InChIKey LNERPLLMHDYJTB-UHFFFAOYSA-N
SMILES COC1=C(OC)C(=O)C(C(C)(C)CC(=O)NCCCNCCCCNCCCN)=C(C)C1=O.Cl.Cl.Cl
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