N-acetylspermine

Modify Date: 2024-01-02 22:53:04

N-acetylspermine Structure
N-acetylspermine structure
Common Name N-acetylspermine
CAS Number 25593-72-0 Molecular Weight 244.37700
Density 0.962g/cm3 Boiling Point 442.9ºC at 760 mmHg
Molecular Formula C12H28N4O Melting Point N/A
MSDS N/A Flash Point 221.7ºC

 Use of N-acetylspermine


N1-Acetylspermine is an endogenous metabolite present in Urine that can be used for the research of Leukemia[1][2].

 Names

Name N1-acetylspermine
Synonym More Synonyms

 N-acetylspermine Biological Activity

Description N1-Acetylspermine is an endogenous metabolite present in Urine that can be used for the research of Leukemia[1][2].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  

[2]. Lee SH, et al. Polyamine profiles in the urine of patients with leukemia. Cancer Lett. 1998 Jan 9;122(1-2):1-8.  

 Chemical & Physical Properties

Density 0.962g/cm3
Boiling Point 442.9ºC at 760 mmHg
Molecular Formula C12H28N4O
Molecular Weight 244.37700
Flash Point 221.7ºC
Exact Mass 244.22600
PSA 82.67000
LogP 2.14320
Vapour Pressure 4.84E-08mmHg at 25°C
Index of Refraction 1.479

 Safety Information

Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36
HS Code 2924199090

 Synthetic Route

~33%

N-acetylspermine Structure

N-acetylspermine

CAS#:25593-72-0

Literature: Franceschin, Marco; Lombardo, Caterina Maria; Pascucci, Emanuela; D'Ambrosio, Danilo; Micheli, Emanuela; Bianco, Armandodoriano; Ortaggi, Giancarlo; Savino, Maria Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 5 p. 2292 - 2304

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

N-[3-[4-(3-aminopropylamino)butylamino]propyl]acetamide
n-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]acetamid
N'-Monoacetylspermine
N(1)-acetylspermine
N-Acetylspermine
N(1)-Acetylspermine