CDK2
Modify Date: 2024-01-03 17:49:37
CDK2 structure
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Common Name | CDK2 | ||
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| CAS Number | 255064-79-0 | Molecular Weight | 831.92 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H57N15O9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CDK2CDK2 is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. |
| Name | CDK2 |
|---|
| Description | CDK2 is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. |
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| Related Catalog | |
| In Vitro | CDK2 (Cyclin-dependent kinase 2) is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. The fully active CDK2 is in complex with HHASPRK (an optimal peptide substrate), namely interactions of CDK2 with peptide substrate and the dynamics of the G-loop. CDK2 participates in eukaryotic cell cycle regulation at the G1/S boundary. CDK2 deregulation has been proved to occur in tumor cells, evoking a strong interest in artificial and native inhibitors. CDK2 activity is tightly regulated by a complex mechanism, including a positive regulatory subunit binding, and phosphorylations at positive and/or negative regulatory sites[1]. |
| References |
| Molecular Formula | C35H57N15O9 |
|---|---|
| Molecular Weight | 831.92 |
| Storage condition | 2-8℃ |