CDK2-IN-11

Modify Date: 2024-01-08 11:54:36

CDK2-IN-11 structure	Common Name	CDK2-IN-11
	CAS Number	2410402-82-1	Molecular Weight	427.87
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₄ClN₇O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CDK2-IN-11

CDK2-IN-11 (compound 9d) is a potent CDK2 inhibitor with an IC50 of 6.4 μM, and KI values of 23.4 nM, 56.3 nM and 44.3 nM for hCA II, hCA IX and hCA XII, respectively. CDK2-IN-11 can be used for researching anticancer[1].

Name	CDK2-IN-11

Description	CDK2-IN-11 (compound 9d) is a potent CDK2 inhibitor with an IC50 of 6.4 μM, and KI values of 23.4 nM, 56.3 nM and 44.3 nM for hCA II, hCA IX and hCA XII, respectively. CDK2-IN-11 can be used for researching anticancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	IC50: 6.4 μM (CDK2)[1] KI: 23.4 nM (hCA II), 56.3 nM (hCA IX), 44.3 nM (hCA XII)[1]
References	[1]. Said MA, et al. Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation. Eur J Med Chem. 2020 Mar 1;189:112019.

Molecular Formula	C₁₈H₁₄ClN₇O₂S
Molecular Weight	427.87

CDK2-IN-11

Use of CDK2-IN-11

Names

CDK2-IN-11 Biological Activity

Chemical & Physical Properties