2841405-96-5
2841405-96-5 structure
- Name: EGFR/CDK2-IN-1
- Chemical Name: EGFR/CDK2-IN-1
- CAS Number: 2841405-96-5
- Molecular Formula: C19H12BrClO2
- Molecular Weight: 387.65
- Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
- Create Date: 2022-11-29 16:38:39
- Modify Date: 2024-01-09 19:05:50
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EGFR/CDK2-IN-1 (Compound 3b) is an EGFR/CDK2 inhibitor. EGFR/CDK2-IN-1 shows good cytotoxicity against MCF7 and HepG2 cells. EGFR/CDK2-IN-1 can be used in cancer research[1].
| Name | EGFR/CDK2-IN-1 |
|---|
| Description | EGFR/CDK2-IN-1 (Compound 3b) is an EGFR/CDK2 inhibitor. EGFR/CDK2-IN-1 shows good cytotoxicity against MCF7 and HepG2 cells. EGFR/CDK2-IN-1 can be used in cancer research[1]. |
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| Related Catalog | |
| Target |
EGFR, CDK-2[1]. |
| In Vitro | EGFR/CDK2-IN-1 (0-20 μM; 48 h) shows excellent activity in both MCF7 and HepG2 with IC50 values of 4.1 and 3.5 μM, respectively[1]. Cell Cytotoxicity Assay[1] Cell Line: MCF7, HepG2 cells Concentration: 0-20 μM Incubation Time: 48 h Result: Exhibited good cytotoxic activity in breast and liver cancer cells. |
| Molecular Formula | C19H12BrClO2 |
|---|---|
| Molecular Weight | 387.65 |