DNA Gyrase-IN-2

Modify Date: 2025-08-21 13:13:18

DNA Gyrase-IN-2 structure	Common Name	DNA Gyrase-IN-2
	CAS Number	2522666-80-2	Molecular Weight	504.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₄N₈OS₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DNA Gyrase-IN-2

DNA Gyrase-IN-2 (Compound 22a) is a bacterial DNA gyrase B inhibitor with IC50s of 3.29-10.49 and 4.41-5.61 µM for E. coli DNA gyrase and M. tuberculosis DNA gyrase. Anti-tubercular and antibacterial activity[1].

Name	DNA Gyrase-IN-2

Description	DNA Gyrase-IN-2 (Compound 22a) is a bacterial DNA gyrase B inhibitor with IC50s of 3.29-10.49 and 4.41-5.61 µM for E. coli DNA gyrase and M. tuberculosis DNA gyrase. Anti-tubercular and antibacterial activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Mohamed A Omar, et al. Novel anti-tubercular and antibacterial based benzosuberone-thiazole moieties: Synthesis, molecular docking analysis, DNA gyrase supercoiling and ATPase activity. Bioorg Chem. 2020 Nov;104:104316.

Molecular Formula	C₂₄H₂₄N₈OS₂
Molecular Weight	504.63

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