BRAF V600E/CRAF-IN-1

Modify Date: 2025-08-26 08:57:49

BRAF V600E/CRAF-IN-1 structure	Common Name	BRAF V600E/CRAF-IN-1
	CAS Number	2499499-56-6	Molecular Weight	505.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₁₇F₆N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BRAF V600E/CRAF-IN-1

BRAF V600E/CRAF-IN-1 (Compound 8b) is a potent inhibitor of BRAF V600E/CRAF. BRAF V600E/CRAF-IN-1 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-1 has the potential for the research of cancer diseases[1].

Name	BRAF V600E/CRAF-IN-1

Description	BRAF V600E/CRAF-IN-1 (Compound 8b) is a potent inhibitor of BRAF V600E/CRAF. BRAF V600E/CRAF-IN-1 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-1 has the potential for the research of cancer diseases[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> Raf
References	[1]. El-Damasy AK, et al. 2-Anilinoquinoline based arylamides as broad spectrum anticancer agents with B-RAFV600E/C-RAF kinase inhibitory effects: Design, synthesis, in vitro cell-based and oncogenic kinase assessments. Eur J Med Chem. 2020 Dec 15;208:112756.

Molecular Formula	C₂₅H₁₇F₆N₃O₂
Molecular Weight	505.41
InChIKey	ZOFPYTOXNJKYQJ-UHFFFAOYSA-N
SMILES	COc1cccc2nc(Nc3cccc(NC(=O)c4cc(C(F)(F)F)cc(C(F)(F)F)c4)c3)ccc12

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BRAF V600E/CRAF-IN-1

Use of BRAF V600E/CRAF-IN-1

Names

BRAF V600E/CRAF-IN-1 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.