LC kinetic stabilizer-1

Modify Date: 2025-09-21 18:59:54

LC kinetic stabilizer-1 structure	Common Name	LC kinetic stabilizer-1
	CAS Number	2495750-19-9	Molecular Weight	473.57
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₁N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LC kinetic stabilizer-1

LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL* and WIL-FL* T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer[1].

Name	LC kinetic stabilizer-1

Description	LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL* and WIL-FL* T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Yan NL, et al. Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site. Bioorg Med Chem Lett. 2022;60:128571.

Molecular Formula	C₂₇H₃₁N₅O₃
Molecular Weight	473.57
InChIKey	HZXLPUWIDZEPQG-UHFFFAOYSA-N
SMILES	CCN(CC)c1ccc2c(C)c(CCNC(=O)NCc3cccc(-c4cnc[nH]4)c3)c(=O)oc2c1

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China
Product Name: LC kinetic stabilizer-1
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China
Product Name: LC kinetic stabilizer-1
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.