Auramine O

Modify Date: 2025-08-22 17:33:52

Auramine O structure	Common Name	Auramine O
	CAS Number	2465-27-2	Molecular Weight	303.830
	Density	1.01g/cm3	Boiling Point	406.2ºC at 760mmHg
	Molecular Formula	C₁₇H₂₂ClN₃	Melting Point	>250 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	199.4ºC
	Symbol	GHS06, GHS08	Signal Word	Danger

Use of Auramine O

Auramine O is a yellow fluorescent dye and can be used to stain acid-fast bacteria. Auramine O is toxic and resistant in the environment[1][2].

Name	auramine O
Synonym	More Synonyms

Description	Auramine O is a yellow fluorescent dye and can be used to stain acid-fast bacteria. Auramine O is toxic and resistant in the environment[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Kommareddi S, et al. Nontuberculous mycobacterial infections: comparison of the fluorescent auramine-O and Ziehl-Neelsen techniques in tissue diagnosis. Hum Pathol. 1984 Nov;15(11):1085-9. [2]. Hosseinpour S A, et al. Use of metal composite MOF‐5‐Ag2O‐NPs as an adsorbent for the removal of Auramine O dye under ultrasound energy conditions. Applied Organometallic Chemistry, 2018, 32(2): e4007.

Description

Auramine O is a yellow fluorescent dye and can be used to stain acid-fast bacteria. Auramine O is toxic and resistant in the environment[1][2].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Kommareddi S, et al. Nontuberculous mycobacterial infections: comparison of the fluorescent auramine-O and Ziehl-Neelsen techniques in tissue diagnosis. Hum Pathol. 1984 Nov;15(11):1085-9.

[2]. Hosseinpour S A, et al. Use of metal composite MOF‐5‐Ag2O‐NPs as an adsorbent for the removal of Auramine O dye under ultrasound energy conditions. Applied Organometallic Chemistry, 2018, 32(2): e4007.

Density	1.01g/cm3
Boiling Point	406.2ºC at 760mmHg
Melting Point	>250 °C (dec.)(lit.)
Molecular Formula	C₁₇H₂₂ClN₃
Molecular Weight	303.830
Flash Point	199.4ºC
Exact Mass	303.150238
PSA	30.33000
LogP	4.13650
Vapour Pressure	8.31E-07mmHg at 25°C

Auramine O MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BY3675000

CHEMICAL NAME :: Aniline, 4,4'-(imidocarbonyl)bis(N,N-dimethyl-, hydrochloride

CAS REGISTRY NUMBER :: 2465-27-2

LAST UPDATED :: 199710

DATA ITEMS CITED :: 32

MOLECULAR FORMULA :: C17-H21-N3.Cl-H

MOLECULAR WEIGHT :: 303.87

WISWESSER LINE NOTATION :: 1N1&R DYUM&R DN1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 480 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - domestic

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 40 gm/kg/87W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 440 mg/kg/21W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 73 gm/kg/52W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 32760 mg/kg/39W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: Morphological transformation

TYPE OF TEST :: DNA damage

TYPE OF TEST :: DNA damage

TYPE OF TEST :: Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 20 umol/L/5H (Continuous)

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,27,1979 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FRANCE;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1444 No. of Facilities: 1184 (estimated) No. of Industries: 17 No. of Occupations: 22 No. of Employees: 10114 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1444 No. of Facilities: 1191 (estimated) No. of Industries: 27 No. of Occupations: 24 No. of Employees: 19092 (estimated) No. of Female Employees: 4705 (estimated)

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H302-H311-H351
Precautionary Statements	P280-P312
Hazard Codes	T:Toxic
Risk Phrases	R22;R24;R40
Safety Phrases	S36/37-S45
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	BY3675000
Hazard Class	6.1
HS Code	2925290090

HS Code	2925290090
Summary	2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Functional and genetic characterization of the tap efflux pump in Mycobacterium bovis BCG.

Antimicrob. Agents Chemother. 56(4) , 2074-83, (2012)

Efflux pumps extrude a wide variety of chemically unrelated compounds conferring multidrug resistance and participating in numerous physiological processes. Mycobacterium tuberculosis possesses many e...

Confocal laser scanning microscopy elucidation of the micromorphology of the leaf cuticle and analysis of its chemical composition.

Protoplasma 252 , 1475-86, (2015)

Electron microscopy techniques such as transmission electron microscopy (TEM) and scanning electron microscopy (SEM) have been invaluable tools for the study of the micromorphology of plant cuticles. ...

Efficacy of real-time polymerase chain reaction for rapid diagnosis of endobronchial tuberculosis

Int. J. Infect. Dis. 27 , 13-7, (2014)

• We assess the efficacy of realtime PCR of bronchial biopsies for diagnosis of EBTB • Real-time PCR yields better than AFB staining of bronchial brushing or sputum smear • Bronchoscopic types of EBTB...

Hydrogen chloride - 4,4'-carbonimidoylbis(N,N-dimethylaniline) (1:1:1)

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Auramine O
Price: Check
Purity: 70.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Auramine O
Price: ￥158.0/100g
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Auramine hydrochloride
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Basic Yellow 2
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: AURAMINE O
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Auramine O

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

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MUTATION DATA

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.