ALV1
Modify Date: 2025-08-25 19:29:59
ALV1 structure
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Common Name | ALV1 | ||
|---|---|---|---|---|
| CAS Number | 2438124-79-7 | Molecular Weight | 494.93 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H23ClN4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ALV1ALV1 is a potent Ikaros and Helios degrader. ALV1 potently reduces the protein abundance of IKZF1-4, CK1α (casein kinase 1α, CSNK1A1) and ribosomal protein RPL4. ALV1 shows similar degradation activity towards IKZF1/2/3. ALV1 induced Helios/CRBN dimerization. ALV1 promoted IL-2 secretion to a great extent[1]. |
| Name | ALV1 |
|---|
| Description | ALV1 is a potent Ikaros and Helios degrader. ALV1 potently reduces the protein abundance of IKZF1-4, CK1α (casein kinase 1α, CSNK1A1) and ribosomal protein RPL4. ALV1 shows similar degradation activity towards IKZF1/2/3. ALV1 induced Helios/CRBN dimerization. ALV1 promoted IL-2 secretion to a great extent[1]. |
|---|---|
| Related Catalog | |
| Target |
CK1α |
| References |
| Molecular Formula | C25H23ClN4O5 |
|---|---|
| Molecular Weight | 494.93 |
| InChIKey | YDYSAFPHVGVORZ-UHFFFAOYSA-N |
| SMILES | Cc1ccc(NC(=O)CCc2cccc(NC3=CC(=O)N(C4CCC(=O)NC4=O)C3=O)c2)cc1Cl |