TP0586532

Modify Date: 2024-04-06 08:17:24

TP0586532 Structure
TP0586532 structure
Common Name TP0586532
CAS Number 2427584-96-9 Molecular Weight 460.52
Density N/A Boiling Point N/A
Molecular Formula C26H28N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TP0586532


TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].

 Names

Name TP0586532

 TP0586532 Biological Activity

Description TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].
Related Catalog
Target

IC50: 0.101 μM (non-hydroxamate LpxC)[1]

In Vitro TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].
References

[1]. Ushiyama F, et al. Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg Med Chem. 2021;30:115964.

 Chemical & Physical Properties

Molecular Formula C26H28N4O4
Molecular Weight 460.52
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