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2427584-96-9

2427584-96-9 structure
2427584-96-9 structure
  • Name: TP0586532
  • Chemical Name: TP0586532
  • CAS Number: 2427584-96-9
  • Molecular Formula: C26H28N4O4
  • Molecular Weight: 460.52
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2021-11-02 21:48:37
  • Modify Date: 2024-04-06 08:17:24
  • TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].

Name TP0586532
Description TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].
Related Catalog
Target

IC50: 0.101 μM (non-hydroxamate LpxC)[1]

In Vitro TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].
References

[1]. Ushiyama F, et al. Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg Med Chem. 2021;30:115964.

Molecular Formula C26H28N4O4
Molecular Weight 460.52