solifenacin succinate

Modify Date: 2025-08-24 01:21:31

solifenacin succinate Structure
solifenacin succinate structure
 Common Name solifenacin succinate
CAS Number 242478-38-2 Molecular Weight 480.553
Density 1.24g/cm3 Boiling Point 505.5ºC at 760 mmHg
Molecular Formula C27H32N2O6 Melting Point 147 °C
MSDS N/A Flash Point 259.5ºC

 Use of solifenacin succinate


Solifenacin Succinate(YM905; Vesicare) is a muscarinic receptor antagonist.IC50 value:Target: muscarinic receptorSolifenacin succinate (YM905; Vesicare) is a prescription medication used to treat certain bladder problems.

 Names

Name Solifenacin succinate
Synonym More Synonyms

 solifenacin succinate Biological Activity

Description Solifenacin Succinate(YM905; Vesicare) is a muscarinic receptor antagonist.IC50 value:Target: muscarinic receptorSolifenacin succinate (YM905; Vesicare) is a prescription medication used to treat certain bladder problems.
Related Catalog
References

[1]. Krishna SR, Rao BM, Rao NS.A validated rapid stability-indicating method for the determination of related substances in solifenacin succinate by ultra-fast liquid chromatography.J Chromatogr Sci. 2010 Nov;48(10):807-10.

[2]. Ohtake A, Sato S, Sasamata M, Miyata K.The forefront for novel therapeutic agents based on the pathophysiology of lower urinary tract dysfunction: ameliorative effect of solifenacin succinate (Vesicare), a bladder-selective antimuscarinic agent, on overactive bladder symptoms, especially urgency episodes.J Pharmacol Sci. 2010;112(2):135-41. Epub 2010 Feb 4.

[3]. Hoffstetter S, Leong FC.Solifenacin succinate for the treatment of overactive bladder.Expert Opin Drug Metab Toxicol. 2009 Mar;5(3):345-50.

[4]. Choo MS, Lee JZ, Lee JB, Kim YH, Jung HC, Lee KS, Kim JC, Seo JT, Paick JS, Kim HJ, Na YG, Lee JG.Efficacy and safety of solifenacin succinate in Korean patients with overactive bladder: a randomised, prospective, double-blind, multicentre study.Int J Clin Pract. 2008 Nov;62(11):1675-83.

[5]. Imamura T, et al.Combined treatment with a β3 -adrenergic receptor agonist and a muscarinic receptor antagonist inhibits detrusor overactivity induced by cold stress in spontaneously hypertensive rats. Neurourol Urodyn. 2017 Apr;36(4):1026-1033.

 Chemical & Physical Properties

Density 1.24g/cm3
Boiling Point 505.5ºC at 760 mmHg
Melting Point 147 °C
Molecular Formula C27H32N2O6
Molecular Weight 480.553
Flash Point 259.5ºC
Exact Mass 480.226044
PSA 107.38000
LogP 3.67650
Vapour Pressure 2.41E-10mmHg at 25°C
Index of Refraction 1.648
InChIKey RXZMMZZRUPYENV-VROPFNGYSA-N
SMILES O=C(O)CCC(=O)O.O=C(OC1CN2CCC1CC2)N1CCc2ccccc2C1c1ccccc1

 Safety Information

Hazard Codes Xi

 Synonyms

1-Azabicyclo[2.2.2]octan-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate butanedioic acid
(1R,3R)-1-azabicyclo[2.2.2]octan-3-yl (1S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
(3R)-1-Azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate butanedioate
2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester, (1S)-, butanedioate (1:1)
Succinic acid - (3R)-1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydro-2(1H)-isoquinolinecarboxylate (1:1)
solifenacin succinate
Vesikur
Solifenacin succinate [USAN]
T66 CNT&J BR& CVO- AT66 A B CNTJ &&(1S)-(3R)- Form succinate
Butanedioic acid, compd with (1S)-(3R)-1-azabicyclo(2.2.2)oct-3-yl 3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate (1:1)
IsoprenalinoeSulfate
(1S)-(3R)-1-Azabicyclo[2.2.2]oct-3-yl 3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate Butanedioic Acid
Vesicare
Solifenacin (Succinate)
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Related Compounds: More...
(R,R)-Solifenacin Succinate
862207-70-3
Solifenacin Related CoMpound 2 Succinate
1262506-09-1
Solifenacin Related Compound 18
1225338-27-1
Solifenacin IMpurity
1956436-64-8
Solifenacin Related Compound 19
1427376-05-3
Solifenacin N-Oxide
180272-28-0
Solifenacin D5 hydrochloride
1426174-05-1
solifenacin
242478-37-1
Solifenacin Related Compound 13
1251905-45-9
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2877703-35-8
6-methyl-N-(1-{[4-(trifluoromethyl)phenyl]methyl}piperidin-4-yl)pyrimidin-4-amine
2877765-25-6
(3aS,3bS,9aR,9bS,10S,11aS)-5',5',11a-Trimethyl-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydrospiro[cyclopenta[a]phenanthrene-1,2'-[1,3]dioxan]-10-ol
1182723-62-1
4-(Difluoromethyl)-2-methyl-6-[4-(2-phenylethyl)piperazine-1-carbonyl]pyrimidine
2877711-87-8
4-{4-[(5-Fluoropyridin-3-yl)methyl]piperazin-1-yl}-2-(methylsulfanyl)pyrimidine
2877669-26-4
6-(difluoromethyl)-N-(3-methoxyphenyl)-2-methylpyrimidine-4-carboxamide
2877666-20-9
6-(difluoromethyl)-N-(4-methoxyphenyl)-2-methylpyrimidine-4-carboxamide
2877657-25-3
4-(4-{4H,5H,6H-cyclopenta[d][1,3]thiazol-2-yl}piperazin-1-yl)-6-(trifluoromethyl)pyrimidine
2877680-56-1
4-Ethyl-5-fluoro-2-(2,2,2-trifluoroacetamido)benzoic acid
2764005-57-2
Carbamic acid, benzylmethyldithio-, (4-amino-2-methyl-5-pyrimidinyl)methyl ester
25386-60-1
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