Sevasemten

Modify Date: 2025-08-25 09:58:38

Sevasemten structure	Common Name	Sevasemten
	CAS Number	2417395-15-2	Molecular Weight	381.28
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₁F₄N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Sevasemten

Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with IC50s of ≤10 μM (skeletal), >100 μM (cardiac), respectively[1][2].

Name	Sevasemten

Description	Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with IC50s of ≤10 μM (skeletal), >100 μM (cardiac), respectively[1][2].
Related Catalog	Signaling Pathways >> Cytoskeleton >> Myosin Research Areas >> Others
References	[1]. Russell Alan, et al. Preparation of substituted pyridazinones for use in the treatment of neuromuscular diseases: World Intellectual Property Organization, WO2021231615. 2021-11-18. [2]. WHO Drug Information-World Health Organization (WHO).

Description

Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with IC50s of ≤10 μM (skeletal), >100 μM (cardiac), respectively[1][2].

Related Catalog

Signaling Pathways >> Cytoskeleton >> Myosin

Research Areas >> Others

References

[1]. Russell Alan, et al. Preparation of substituted pyridazinones for use in the treatment of neuromuscular diseases: World Intellectual Property Organization, WO2021231615. 2021-11-18.

[2]. WHO Drug Information-World Health Organization (WHO).