Sevasemten

Names

[ Name ]:
Sevasemten

Biological Activity

[Description]:

Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with IC50s of ≤10 μM (skeletal), >100 μM (cardiac), respectively[1][2].

[Related Catalog]:

Signaling Pathways >> Cytoskeleton >> Myosin

Research Areas >> Others

[References]

[1]. Russell Alan, et al. Preparation of substituted pyridazinones for use in the treatment of neuromuscular diseases: World Intellectual Property Organization, WO2021231615. 2021-11-18.

[2]. WHO Drug Information-World Health Organization (WHO).

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₁F₄N₅O₂

[ Molecular Weight ]:
381.28

Related Compounds

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