Sevasemten

Modify Date: 2024-01-29 14:52:05

Sevasemten structure	Common Name	Sevasemten
	CAS Number	2417395-15-2	Molecular Weight	381.28
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₁F₄N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Sevasemten

Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with IC50s of ≤10 μM (skeletal), >100 μM (cardiac), respectively[1][2].

Name	Sevasemten

Description	Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with IC50s of ≤10 μM (skeletal), >100 μM (cardiac), respectively[1][2].
Related Catalog	Signaling Pathways >> Cytoskeleton >> Myosin Research Areas >> Others
References	[1]. Russell Alan, et al. Preparation of substituted pyridazinones for use in the treatment of neuromuscular diseases: World Intellectual Property Organization, WO2021231615. 2021-11-18. [2]. WHO Drug Information-World Health Organization (WHO).

Description

Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with IC50s of ≤10 μM (skeletal), >100 μM (cardiac), respectively[1][2].

Related Catalog

Signaling Pathways >> Cytoskeleton >> Myosin

Research Areas >> Others

References

[1]. Russell Alan, et al. Preparation of substituted pyridazinones for use in the treatment of neuromuscular diseases: World Intellectual Property Organization, WO2021231615. 2021-11-18.

[2]. WHO Drug Information-World Health Organization (WHO).

Molecular Formula	C₁₆H₁₁F₄N₅O₂
Molecular Weight	381.28

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3

Sevasemten

Use of Sevasemten

Names

Sevasemten Biological Activity

Chemical & Physical Properties