Alunacedase alfa

Modify Date: 2024-01-23 17:31:27

Alunacedase alfa Structure
Alunacedase alfa structure
Common Name Alunacedase alfa
CAS Number 2416824-55-8 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Alunacedase alfa


Alunacedase alfa (HrsACE2; GSK 2586881) is a human recombinant soluble angiotensin-converting enzyme-2 (hrsACE2). Alunacedase alfa is a genetically modified soluble form of ACE2, it decreases cell entry of SARS-CoV-2 competing for membrane-bound ACE2. Alunacedase alfa has the potential for the research of SARS-CoV-2[1][2].

 Names

Name Alunacedase alfa

 Alunacedase alfa Biological Activity

Description Alunacedase alfa (HrsACE2; GSK 2586881) is a human recombinant soluble angiotensin-converting enzyme-2 (hrsACE2). Alunacedase alfa is a genetically modified soluble form of ACE2, it decreases cell entry of SARS-CoV-2 competing for membrane-bound ACE2. Alunacedase alfa has the potential for the research of SARS-CoV-2[1][2].
Related Catalog
In Vitro Alunacedase alfa 以大约 1·2 nM 的亲和力与 SARS-CoV-2 的刺突糖蛋白结合[2]。
References

[1]. Abd El-Aziz TM, et al. Human recombinant soluble ACE2 (hrsACE2) shows promise for treating severe COVID-19. Signal Transduct Target Ther. 2020 Nov 3;5(1):258.  

[2]. Zoufaly A, et al. Human recombinant soluble ACE2 in severe COVID-19. Lancet Respir Med. 2020 Nov;8(11):1154-1158.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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