IRE1α kinase-IN-3

Modify Date: 2025-08-26 20:12:51

IRE1α kinase-IN-3 Structure
IRE1α kinase-IN-3 structure
Common Name IRE1α kinase-IN-3
CAS Number 2416223-41-9 Molecular Weight 544.67
Density N/A Boiling Point N/A
Molecular Formula C29H32N6O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IRE1α kinase-IN-3


IRE1α kinase-IN-3 (compound 2) is a potent IRE1α inhibitor with an Ki of 480 nM. IRE1α kinase-IN-3 is the ATP-competitive ligands of IRE1α[1].

 Names

Name IRE1α kinase-IN-3

 IRE1α kinase-IN-3 Biological Activity

Description IRE1α kinase-IN-3 (compound 2) is a potent IRE1α inhibitor with an Ki of 480 nM. IRE1α kinase-IN-3 is the ATP-competitive ligands of IRE1α[1].
Related Catalog
Target

Ki: 480 nM (IRE1α)[1]

References

[1]. Feldman HC, et al. ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR. Nat Chem Biol. 2021 Nov;17(11):1148-1156.

 Chemical & Physical Properties

Molecular Formula C29H32N6O3S
Molecular Weight 544.67
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