Antibacterial agent 83

Modify Date: 2025-08-26 12:07:14

Antibacterial agent 83 structure	Common Name	Antibacterial agent 83
	CAS Number	2413865-92-4	Molecular Weight	282.08
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₅Cl₂N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Antibacterial agent 83

Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes[1].

Name	Antibacterial agent 83

Description	Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Antibacterial agent 83 (compound 17h) 对 Newmana、USA300b、Mu50 均有抗菌作用，MIC 均为0.25 μg/mL[1]。 Antibacterial agent 83 在大鼠、小鼠和犬肝微粒体中稳定性较差[1]。
References	[1]. Huan X, et al. Design, synthesis, and biological evaluations of substituted pyrazoles as pyrrolomycin analogues against staphylococcal biofilm. Eur J Med Chem. 2022 Jun 5;236:114309.

Molecular Formula	C₁₁H₅Cl₂N₃O₂
Molecular Weight	282.08
InChIKey	XTPYKTMUWMXBMC-UHFFFAOYSA-N
SMILES	N#Cc1cc(C(=O)c2cc(Cl)c(Cl)cc2O)[nH]n1

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Antibacterial agent 83

Use of Antibacterial agent 83

Names

Antibacterial agent 83 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.