Antibacterial agent 83

Modify Date: 2025-08-26 12:07:14

Antibacterial agent 83 Structure
Antibacterial agent 83 structure
Common Name Antibacterial agent 83
CAS Number 2413865-92-4 Molecular Weight 282.08
Density N/A Boiling Point N/A
Molecular Formula C11H5Cl2N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antibacterial agent 83


Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes[1].

 Names

Name Antibacterial agent 83

 Antibacterial agent 83 Biological Activity

Description Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes[1].
Related Catalog
In Vitro Antibacterial agent 83 (compound 17h) 对 Newmana、USA300b、Mu50 均有抗菌作用,MIC 均为0.25 μg/mL[1]。 Antibacterial agent 83 在大鼠、小鼠和犬肝微粒体中稳定性较差[1]。
References

[1]. Huan X, et al. Design, synthesis, and biological evaluations of substituted pyrazoles as pyrrolomycin analogues against staphylococcal biofilm. Eur J Med Chem. 2022 Jun 5;236:114309.  

 Chemical & Physical Properties

Molecular Formula C11H5Cl2N3O2
Molecular Weight 282.08
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