2413865-92-4

2413865-92-4 structure

Name: Antibacterial agent 83
Chemical Name: Antibacterial agent 83
CAS Number: 2413865-92-4
Molecular Formula: C₁₁H₅Cl₂N₃O₂
Molecular Weight: 282.08
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2023-05-31 13:10:24
Modify Date: 2025-08-26 12:07:14
Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes[1].

Name	Antibacterial agent 83

Description	Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Antibacterial agent 83 (compound 17h) 对 Newmana、USA300b、Mu50 均有抗菌作用，MIC 均为0.25 μg/mL[1]。 Antibacterial agent 83 在大鼠、小鼠和犬肝微粒体中稳定性较差[1]。
References	[1]. Huan X, et al. Design, synthesis, and biological evaluations of substituted pyrazoles as pyrrolomycin analogues against staphylococcal biofilm. Eur J Med Chem. 2022 Jun 5;236:114309.

Molecular Formula	C₁₁H₅Cl₂N₃O₂
Molecular Weight	282.08